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Tissue Fibrosis

Category Description :

Fibrosis is a devastating disease with limited therapeutic options and involves the activation of multiple pathological pathways.  One of the key pathways is the activation of the TGFb pathway which in turn is negatively regulated by BMP proteins and potentiated by Wnt signaling pathways. MabSpace has programs inhibiting Wnt signaling pathway and enhancing BMP signaling pathway for the treatment of fibrotic disorders for both lung and kidney diseases.



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